REMSTART trial showed that a new approach to HIV management incorporating community support and early screening for cryptococcal meningitis reduced deaths by 28%.

The EMA publishes positive scientific opinion on Pyramax^® based on data from a clinical trial conducted by the WANECAM study.

EDCTP receives Science Diplomacy Award at South African Science Forum

The first EDCTP programme closed in December.

2015

EDCTP and the Amsterdam Institute for Global Health and Development (AIGHD) publish a new Global Roadmap for TB Vaccine R&D, developed in partnership with WHO. New support tools for TB vaccine R&D developed by the Tuberculosis Vaccine Initiative with EDCTP funding are published.

EDCTP and Africa Centres for Disease Control and Prevention launch a major joint regional initiative to train 151 epidemiologists and biostatisticians in Africa. The first epidemiologists and biostatisticians funded through the EDCTP and Africa CDC joint initiative start their master’s training in 2021.

The legal basis for the Global Health EDCTP3 Joint Undertaking is adopted by the European Commission, signalling the start of the third EDCTP programme. 

The Pediatric Praziquantel Consortium announces positive results from its pivotal EDCTP-funded phase III trial of arpraziquantel, a new medication to treat schistosomiasis in preschool-aged children.

A Lancet paper reports that the R21/Matrix-M malaria vaccine showed 77% efficacy in an EDCTP-funded phase IIb trial, becoming the first vaccine to meet the WHO goal of 75% efficacy.

2021

The European Commission publishes the final report of the second interim evaluation of the EDCTP2 programme. The report states that ‘EDCTP2 is highly relevant in the EU and globally’.

EDCTP mourns the loss of Dr Pascoal Mocumbi, EDCTP’s first High Representative. The Dr Pascoal Mocumbi Prize, which is awarded biennially, will be awarded at EDCTP’s Eleventh Forum.

2023

EDCTP joins Europe PubMed Central, an open science platform that maintains a worldwide collection of scientific articles and research outputs. Joining Europe PMC enables EDCTP-funded researchers to share their publications via one central location.

A phase III trial of the AMBITION-cm research team confirms that an alternative formulation of amphotericin B, delivered in tiny lipid-based packages (liposomes), is as good as the current recommended treatment regimen at reducing mortality due to cryptococcal meningitis, a leading cause of HIV–related deaths in sub-Saharan Africa, and has fewer side effects. The results are published in the New England Journal of Medicine.

EDCTP publishes its National Health Research Systems (NHRS) 2020 survey report. The results of the survey show a slight overall improvement in NHRS performance of the EDCTP African participating states.

EDCTP publishes a report on its Fellowship Programme 2003–2022. The report illustrates how EDCTP is making a lasting contribution to the capacity of countries in sub-Saharan Africa.

2022

EDCTP and The Global Health Network launch the EDCTP Knowledge Hub, an open-access resource to support clinical research in low-resource settings.

26 COVID-19 projects awarded, including three with bridging funding from a joint Collaboration Initiative between EDCTP and the Botnar Research Centre for Child Health.

In a joint effort, WHO AFRO and EDCTP publish a roadmap for strengthening of national health research systems. A second national health research system survey is launched.

2020

EDCTP develops new agreements with Novartis International and Fondation Botnar for a career development fellowship scheme focused on maternal, child and adolescent health and wellbeing, and launches a joint call with the Coalition for Epidemic Preparedness Innovations (CEPI) to support the clinical development of Lassa fever vaccines.

EDCTP explores opportunities for collaboration with the European Commission’s Directorate-General for International Cooperation and Development (DEVCO). A strategic call is devised requiring projects to receive co-funding from development cooperation agencies.

EDCTP and Africa Centres for Disease Control and Prevention organise a workshop on gender-related and regional disparities in research and research capacity development in Addis Ababa, Ethiopia.

2019

The PredART trial showed that a readily available drug, prednisone, significantly reduced the risk of TB-IRIS in patients being treated for TB who were starting antiretroviral therapy.

EDCTP Alumni Network launched at a workshop in Johannesburg, South Africa on 3 and 4 October.

Three African countries joined the EDCTP Association: Angola (aspirant member country), Ethiopia and Nigeria

2017

Launch of two EDCTP-funded epidemic research preparedness consortia: ALERRT and PANDORA-ID-NET.

The TRUST project delivers the Global Code of Conduct for Research in Resource-Poor Settings.

EDCTP launches its Emergency Funding initiative for the first time to support research activities in response to the Ebola outbreak in the Democratic Republic of Congo.

2018

In October, EDCTP appointed two High Representatives: Dr Leonardo Santos Simão (High Representative for Africa) and Professor Marcel Tanner (High Representative for Europe).

At the Eighth EDCTP Forum, the Dr Pascoal Mocumbi Prize is awarded for the first time.

2016

The second EDCTP programme (EDCTP2) is launched in Cape Town, South Africa on 2 December.

Historic step: 11 African countries join EDCTP as members.

2014

EFPIA and EDCTP signed a Memorandum of Understanding on a clinical R&D fellowship through placements of sub-Saharan African researchers in European-based pharmaceutical companies.

2013

In March 2012, EDCTP received an EC Coordination and Support Action (CSA) grant. The EDCTP-Plus activities supported by this CSA grant are to consolidate the achievements of the first EDCTP programme and lay the foundation for the second programme.

2012

The 4ABC study supports WHO recommendation of DHAPQ as a treatment for uncomplicated Plasmodium falciparum malaria.

2011

The Kesho Bora study influenced revision of the 2010 WHO guidelines on prevention of mother-to-child transmission of HIV during breastfeeding.

Results from study by EDCTP Senior Fellow Prof. Mark Nicol (South Africa) contributes to WHO endorsement of the Xpert MTB/RIF assay

2010

EDCTP established its integrated approach: a grant scheme that combines clinical trials as a core component with networking and capacity strengthening activities.

The CHAPAS-1 team shared its preliminary pharmacokinetics data with the USA Food and Drug Authority (FDA) and the data contributed to the approval of a paediatric ARV formulation for use in HIV-infected children.

2007

In September, the EDCTP-funded Pan African Clinical Trials Registry (PACTR) was officially recognised as a WHO Primary Registry. PACTR is the only WHO-endorsed primary registry in Africa.

2009

In December, the first of four Networks of Excellence was established: the Central African Network on Tuberculosis, HIV/AIDS and Malaria (CANTAM).

2008

New calls to support the prevention of HIV in Africa were launched, including EDCTP’s first collaboration with Bill & Melinda Gates Foundation: €20M call to support capacity development to prepare for phase II clinical trials of HIV preventive vaccines.

2006

EDCTP launched 8 calls for proposals amounting to more than €20 M. It was the first time EDCTP member country co-funding was introduced for large capacity building and clinical trials calls.

2005

Hosted by NWO, the EDCTP Europe Office opens in The Hague, Netherlands in February 2004. In July, the EDCTP Africa Office was launched in Cape Town, South Africa.

2004